Sure. London, Berlin, New York, Montreal.
There was all kinds of nightlife in all of the neighbourhoods where I lived in Berlin. Sure, it wasn't the "club district" equivalent, which I guess would be the Warschauer Strasse area, but there were all kinds of night spots open considerably later than any in Toronto. They were all very popular and attractive neighbourhoods. My neighbourhood in New York, by contrast, was peaceful and quiet and residential (though very high density) with no nightlife in sight. I can assure you that my rent was a hell of a lot lower than it would have been in the Meatpacking District or Lower East Side, areas that are packed with nightlife. I think a lot of these attitudes are relics of the 1950s/60s ideals of separation of use, as if any commercial (let alone industrial!) presence near a residential neighbourhood would corrupt the children and generally make it a horrible place to live. I just don't really buy it. Mixed use neighbourhoods are great places to live for people who understand what they're getting themselves into. If they really do want silence in the evenings, there are all kinds of lovely neighbourhoods to choose from.
I understand what you're saying, but isn't there some validity to the point that the clubs were there first? Going by myself and my neighbours, I really believe that most people moved into that neighbourhood because they actually like activity and nightlife.
As an aside, I've always found the baseball fans leaving the SkyDome to be just as loud, if not louder, than the clubbers. In fact, I find the biggest noise problem with the clubbers to be horn honking. That could easily be resolved with a no-honking ordinance after, say, 10pm. They have them all over New York and Europe.
The Millennium Park model would be incredibly exciting. I wish that this park could be developed in a similar way. For anybody unfamiliar, what happened in Chicago was that the City wanted to build a parking garage and deck over the rail corridor. The city would build a fairly basic green space, while private donations would be sought for a more elaborate improvement. They were able to raise so much in private donations that they were able to include Cloud Gate and the Gehry bandshell and everything else. The park space should be given over to a charitable foundation with the goal of emulating the Millennium Park model.