Not sure why anyone would be sick of seeing so many Shoppers Drug Mart stores everywhere. Better not move to the US or you'll be seeing Walgreen's like there's no tomorrow.
As mentioned above, Shoppers has a great business model and are hardly a rip off. Their prices are rarely the lowest, but usually middle of the road, or great when on sale and the Optimum card is one of the few incentive cards I'll carry (always need things that are sold at drug stores and it's a good program). They are the best laid out drug stores in all of Canada and cover a lot of different areas without venturing too far from their core business.
More on topic, Shoppers wanted the land where Market Wharf is being built for quite sometime, but the city preferred it to be zoned for mixed use. I would be incredibly surprised if they walked away from this, especially since it is a fantastic opportunity. Location. Location. Location.