It's plain and simple, the city wants a tall beefy skyline (vertical density), and they're getting it.
I think the definition of what a vista actually is has in relation to the debate been lost. Are we speaking on behalf of the architectural vista of a building's exterior? Or the vista outwards from the building?
In the case of 25 The Esplanade, it's west-elevation vista was preserved with the initial building layout skewed in relation to the street. From any other angle, this building is awful, huge strain to the waterfront "vista", completing the physical barrier between city and waterfront to go along with the Gardiner S*it-spressway.
That then, answers the question. Above is my opinion of a vista, someone else may beg to differ.
Conclusion? Vistas are subjective, ranging in scenario from location to location and stylistic/architectural taste from person to person.
Now if that's how I understand the discussion, meanwhile this is about something completely different, this could be a totally subjective answer and we're spinning in circles here folks!