The question is how Richmond and Adelaide Sts will fit into the plan?
Given that those streets' lack of life neither has to do with their width nor the direction of traffic flow, hopefully nothing. Open up new storefronts on the ground floor of the warehouses, bring in some new residents, add a grocery store and a couple of coffee shops and they'll become vibrant pedestrian corridors.
Definitely narrow John and add bike lanes. Perhaps do the same down on Wellington. However, until Toronto adds another 100 km of subway, Adelaide and Richmond are two of only four downtown streets that should be maintained at their current width to keep cars moving.