As noted by fiendishlibrarian, the redevelopment of this area into a mixed-use downtown neighbourhood goes back to 1995 (and probably earlier), and that idea has been supported by mayors, councillors and numerous residents in the area, so it is hardly Adam Vaughan's vision alone. Regardless, the nature of this area will continue to evolve, and that will mean fewer clubs.
What is interesting is that, in effect, you are trying to argue your own self-serving vision for the neighbourhood: a nightclub ghetto. However, that's not what this part of the city is about, nor was it ever all about just clubs.
If anything, one could argue that the excesses of some clubs and too many clubbers - and the resulting poor perception of the area - have crippled the development of this part of town since 1995, but you're not likely not going to see it this way.
Also, given that many people who visit the area to go clubbing don't live in Vaughan's ward, they won't be able to vote for him or against him. And any individual wanting to be a councillor who argues for promoting the sole interests of clubs won't get very far at all.